COVID Phenotyping Assay (CPA) in McLean VA, Alexandria VA, Arlington VA, Bethesda MD, Gaithersburg MD, and Rockville MD
COVID phenotyping assays characterize diverse COVID-19 presentations, enabling personalized understanding and improved patient management. By analyzing various factors such as symptoms, laboratory values, and immunological markers, researchers can identify specific “phenotypes” or subgroups of COVID-19 patients. At Amerimmune Clinic, Dr. Oral Alpan, MD, and his dedicated team offer COVID phenotyping assay that enhances our ability to provide personalized, effective care. By understanding individual immune responses, we are better equipped to manage COVID-19 and support our patients’ health and well-being. For more information, contact us or schedule an appointment online. We have convenient locations to serve you in McLean VA, Alexandria VA, Arlington VA, Bethesda MD, Gaithersburg MD, and Rockville MD.




Table of Contents:
How does a COVID Phenotyping Assay help in understanding an individual’s immune response to the virus?
What types of immune cells or markers are typically analyzed in a COVID Phenotyping Assay?
Who might benefit from undergoing a COVID Phenotyping Assay?
COVID phenotyping assay represents a significant advancement in understanding individual immune responses to SARS-CoV-2, the virus responsible for COVID-19. By offering this sophisticated laboratory test, we provide our patients with detailed insights into their immune system’s functionality, allowing for more informed and tailored healthcare strategies.
Key Immune Cells Analyzed
Our COVID phenotyping assay provides an in-depth analysis of critical immune cells, including:
• T cells: Essential for identifying and eliminating virus-infected cells, these cells are pivotal in managing COVID-19 infections.
• B cells: These cells are vital for antibody production, which neutralizes the virus and prevents further spread.
• Caspase: A family of endoproteases that provide critical links in cell regulatory networks controlling inflammation and cell death.
Comprehensive Immune Parameters
At Amerimmune Clinic, we measure a variety of immune parameters to provide a complete picture of a patient’s immune health:
• T cell activation: Assessing the activation levels of virus-specific T cells helps us understand a patient’s ability to combat the virus effectively.
At Amerimmune Clinic, our commitment to cutting-edge immunological diagnostics enables us to provide personalized insights into the immune response to SARS-CoV-2 through our specialized COVID Phenotyping Assay. This comprehensive analysis helps us understand the intricacies of immune function in COVID-19, guiding our approach to treatment and management.
Immune Cells Assessed at Amerimmune Clinic:
T Cells:
Central to the adaptive immune response, our assay evaluates T-cell subsets to assess their activation, differentiation, and function:
• Helper T cells (CD4+, Th1, Th2, Th17): Critical for coordinating immune responses.
• Cytotoxic T cells (CD8+): Vital for eliminating virus-infected cells.
• Regulatory T cells (Tregs): Essential for preventing autoimmune reactions.
B Cells:
Key players in antibody production, we measure B cell function, including:
• Naive B cells
• Memory B cells
As part of the innate immune system, NK cells provide frontline defense, and our assay evaluates their activation and cytotoxicity.
These cells are involved in pathogen clearance and, crucial for understanding inflammatory responses in severe cases.
Surface Markers:
Surface markers reveal immune cell activation and function. We examine markers such as:
• CD3, CD4, CD8, CD19, CD56
• PD-1, CTLA-4 for T cell exhaustion
• CD38, HLA-DR for immune activation
The COVID Phenotyping Assay is an essential tool that aligns perfectly with our mission to offer targeted and effective treatment solutions. Here’s how it can benefit our patients and community:
Tailored Care for Persistent COVID-19 Symptoms: For patients experiencing prolonged symptoms such as fatigue, brain fog, and muscle aches, our clinic utilizes the COVID Phenotyping Assay COVID Phenotyping Assay to investigate underlying causes. This allows us to develop personalized treatment plans that address specific immune dysfunctions, aiding in symptom relief and recovery.
Support for Long COVID Syndrome Patients: At Amerimmune Clinic, we understand the challenges faced by individuals with Long COVID. The phenotyping assay helps us identify the mechanisms behind their lingering symptoms, enabling us to offer tailored interventions that can improve their quality of life.
Assessment for High-Risk Patients: Our clinic prioritizes the safety of high-risk individuals, including those who are immunocompromised or have underlying health conditions. The assay provides valuable insights into their immune response, allowing us to devise strategies to mitigate the risk of severe complications from COVID-19.
Advancing Research and Treatment: We are committed to contributing to the broader medical community’s understanding of COVID-19. By leveraging data from COVID Phenotyping Assays, our clinic supports ongoing research efforts aimed at developing more effective vaccines and treatments.
Proactive Prevention and Early Intervention: The insights gained from the assay empower us to identify patients’ susceptibility to COVID-19, enabling us to recommend preventive measures and early interventions that can reduce the risk of infection and its complications.
COVID Phenotyping Assay (CPA) available at Amerimmune Clinic. For more information, contact us or schedule an appointment online. We have convenient locations to serve you. We serve patients from McLean VA, Alexandria VA, Arlington VA, Bethesda MD, Gaithersburg MD, Rockville MD, Vienna VA, IdylWood VA, Lincolnia VA, Groveton VA, Falls Church VA, North Bethesda MD, Takoma Park MD, Montgomery Village MD, Redland MD, Aspen Hill MD, and surrounding areas.
AMERIMMUNE’S COVID PHENOTYPING ASSAY (CPA) IS DESIGNED TO EVALUATE THE IMMUNE CELLS AND COMPONENTS THAT ARE CRITICAL IN THE HOST IMMUNE RESPONSE AND CONTROLLING INFLAMMATION, IDENTIFYING AREAS OF DEFICIENCY, OVERACTIVITY, AND DYSFUNCTION IN THE IMMUNE SYSTEM. CPA WILL REVEAL HIGH RISK FOR SEVERE DISEASE FROM SARS-COV-2 BY IDENTIFYING IMMUNE DEFICIENCIES AS PER CDC GUIDELINES.
Markers include: LAG-3, PD-1, Caspase 1 inhibitor, ICOS, HLA-DR, CD3, CD4, CD45RA, CD45RO, CD38, CD28, CD8, CD45, CXCR5, CCR5, CD39, CD127, CCR7, CD25, CD317, CD27, CD19, CD20

Additional Services You May Need
▸ Allergy Consultation
▸ Immunology Consultation
▸ Allergen Immunotherapy
▸ Allergy Vials
▸ Allergy Shots
▸ Biological Drug Administration
▸ Diagnostic Testing
▸ Skin Prick Testing
▸ Allergy Patch Testing
▸ Oral Food Challenge Testing
▸ Nasal Swab Culture Testing
▸ Routine Venipuncture Testing
▸ Telehealth
▸ Immunology Testing
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Additional Services You May Need
▸ Allergy Consultation
▸ Immunology Consultation
▸ Allergen Immunotherapy
▸ Allergy Vials
▸ Allergy Shots
▸ Biological Drug Administration
▸ Diagnostic Testing
▸ Skin Prick Testing
▸ Allergy Patch Testing
▸ Oral Food Challenge Testing
▸ Nasal Swab Culture Testing
▸ Routine Venipuncture Testing
▸ Telehealth
▸ Immunology Testing
▸ Food Allergy Testing